Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.67 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | HPGD | P15428 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701170 | 0.81 | TAS1R3 (1.00) | TAS1R3TAS1R1POLBALDH1A1HPGD | |
| SCHEMBL14817128 | 0.80 | TAS1R3 (0.76) | TAS1R3TAS1R1POLBALDH1A1HPGD | |
| SCHEMBL31016553 | 0.77 | TAS1R3 (0.64) | TAS1R3TAS1R1POLBALDH1A1HPGD | |
| SCHEMBL8829977 | 0.75 | TAS1R3 (0.68) | TAS1R3TAS1R1POLBALDH1A1HPGD | |
| SCHEMBL10915036 | 0.74 | CNR1 (0.61) | TAS1R3TAS1R1POLBALDH1A1HPGD | |
| SCHEMBL23139885 | 0.73 | ALDH1A1 (0.61) | TAS1R3TAS1R1POLBALDH1A1HPGD | |
| SCHEMBL29209631 | 0.72 | APLNR (0.59) | TAS1R3TAS1R1POLBALDH1A1HPGD | |
| SCHEMBL24499498 | 0.72 | APLNR (0.59) | TAS1R3TAS1R1POLBALDH1A1HPGD | |
| SCHEMBL2226085 | 0.72 | APLNR (0.59) | TAS1R3TAS1R1POLBALDH1A1HPGD | |
| SCHEMBL2223385 | 0.72 | ALDH1A1 (0.59) | TAS1R3TAS1R1POLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616711-A | REACTING BUTENE DERIVATIVE TO AN AMIDE DERIVATIVE; USEFUL AS INTERMEDIATES FOR PRODUCING ANTIULCER DRUGS | FUJIREBIO INC. (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0582304-A2 | Methods of producing amino butene derivatives | FUJIREBIO Inc. (JP) | 1994-02-09 | — | — | EP | disclosed |