Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8829955 | 0.81 | ALDH1A1 (0.45) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8829986 | 0.78 | ALDH1A1 (0.44) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL28013353 | 0.77 | TDP1 (0.50) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL18905578 | 0.76 | RAB9A (0.64) | ALDH1A1POLBRAB9ALMNAHPGD | |
| SCHEMBL8829973 | 0.74 | CTSS (0.46) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8829943 | 0.73 | KMT2A (0.41) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL236223 | 0.72 | ALDH1A1 (0.54) | ALDH1A1POLBMEN1KMT2ARAB9A | |
| SCHEMBL124124 | 0.72 | ALDH1A1 (0.45) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1490952 | 0.72 | HPGD (0.76) | ALDH1A1POLBRAB9ALMNAHPGD | |
| Hydrochloric Acid SCHEMBL27401794 | 0.71 | ALDH1A1 (0.52) | ALDH1A1POLBMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616711-A | REACTING BUTENE DERIVATIVE TO AN AMIDE DERIVATIVE; USEFUL AS INTERMEDIATES FOR PRODUCING ANTIULCER DRUGS | FUJIREBIO INC. (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0582304-A2 | Methods of producing amino butene derivatives | FUJIREBIO Inc. (JP) | 1994-02-09 | — | — | EP | disclosed |