Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8829986 | 0.86 | ALDH1A1 (0.44) | RAB9ASMN1; SMN2GAAALDH1A1MAPT | |
| SCHEMBL7346627 | 0.82 | CTSS (0.47) | CTSSCTSKRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8829955 | 0.80 | ALDH1A1 (0.45) | RAB9ANPC1GAAALDH1A1MAPT | |
| SCHEMBL5549021 | 0.78 | CTSS (0.52) | CTSSCTSKRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL24831465 | 0.76 | CTSS (0.50) | CTSSCTSKRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL216619 | 0.75 | HSD17B10 (0.60) | CTSSCTSKRAB9ASMN1; SMN2GAA | |
| SCHEMBL8829971 | 0.74 | GAA (0.50) | RAB9ASMN1; SMN2NPC1GAAALDH1A1 | |
| SCHEMBL8829970 | 0.73 | ALDH1A1 (0.55) | CTSSCTSKRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5322951 | 0.72 | CTSS (0.49) | CTSSCTSKRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28793821 | 0.71 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616711-A | REACTING BUTENE DERIVATIVE TO AN AMIDE DERIVATIVE; USEFUL AS INTERMEDIATES FOR PRODUCING ANTIULCER DRUGS | FUJIREBIO INC. (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0582304-A2 | Methods of producing amino butene derivatives | FUJIREBIO Inc. (JP) | 1994-02-09 | — | — | EP | disclosed |