Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL266148 | 0.79 | KMT2A (0.58) | ALDH1A1KDM4ENPC1GAAHSD17B10 | |
| SCHEMBL26359012 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4ENPC1GAAHSD17B10 | |
| SCHEMBL14685183 | 0.76 | KDM4E (0.56) | ALDH1A1KDM4ENPC1GAAHSD17B10 | |
| SCHEMBL18459077 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KDM4ENPC1GAAHSD17B10 | |
| SCHEMBL9923883 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4ENPC1GAAHSD17B10 | |
| SCHEMBL25889552 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KDM4ENPC1GAAHSD17B10 | |
| SCHEMBL6479532 | 0.76 | KMT2A (0.54) | ALDH1A1KDM4ENPC1GAAHSD17B10 | |
| SCHEMBL6479440 | 0.73 | KDM4E (0.49) | ALDH1A1KDM4ENPC1GAAHSD17B10 | |
| SCHEMBL297730 | 0.73 | ALDH1A1 (0.50) | ALDH1A1KDM4ENPC1GAAHSD17B10 | |
| SCHEMBL12349885 | 0.73 | NPC1 (0.76) | ALDH1A1KDM4ENPC1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670526-A | ANTIINFLAMMATORY AGENT, IMMUNOSUPPRESSANT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |