SCHEMBL266148

SCHEMBL266148

Cc1nc2ccccn2c1C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.58
KDM4E B2RXH2 6/20 0.56
ALDH1A1 P00352 6/20 0.56
HSD17B10 Q99714 5/20 0.56
GAA P10253 3/20 0.56
HPGD P15428 3/20 0.56
NPC1 O15118 2/20 0.56
GLA P06280 1/20 0.56
CASP1 P29466 1/20 0.56
CASP7 P55210 1/20 0.56
NPSR1 Q6W5P4 5/20 0.54
MAPT P10636 1/20 0.54
RAB9A P51151 1/20 0.54
MAPK1 P28482 1/20 0.50
MEN1 O00255 1/20 0.50
CDK4 P11802 1/20 0.49
CDK2 P24941 1/20 0.49
LMNA P02545 1/20 0.47
CRHBP P24387 1/20 0.47
CRHR2 Q13324 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26359012 0.81 ALDH1A1 (0.54) KMT2AKDM4EALDH1A1HSD17B10GAA
SCHEMBL15004608 0.81 KMT2A (0.61) KMT2AKDM4EALDH1A1HSD17B10GAA
SCHEMBL6479532 0.79 KMT2A (0.54) KMT2AKDM4EALDH1A1HSD17B10GAA
SCHEMBL7965109 0.79 KMT2A (0.54) KMT2AKDM4EALDH1A1HSD17B10GAA
SCHEMBL14685183 0.79 KDM4E (0.56) KMT2AKDM4EALDH1A1HSD17B10GAA
SCHEMBL15004600 0.79 NPC1 (0.58) KMT2AKDM4EALDH1A1HSD17B10GAA
SCHEMBL18901345 0.79 KMT2A (0.54) KMT2AKDM4EALDH1A1HSD17B10GAA
SCHEMBL8829992 0.79 ALDH1A1 (0.52) KMT2AKDM4EALDH1A1HSD17B10GAA
SCHEMBL792006 0.79 KMT2A (0.59) KMT2AKDM4EALDH1A1HSD17B10GAA
SCHEMBL25889552 0.79 ALDH1A1 (0.52) KMT2AKDM4EALDH1A1HSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243194-A1 ANTAGONIST OF ADENOSINE RECEPTORS JANSSEN PHARMACEUTICA NV (BE) 2025-07-31 US disclosed
US-20240208952-A1 THIOPHENE GLP-1 RECEPTOR AGONIST AND USE THEREOF HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL CO., LTD. (CN) 2024-06-27 US disclosed
US-20240208952-A1 THIOPHENE GLP-1 RECEPTOR AGONIST AND USE THEREOF HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL CO., LTD. (CN) 2024-06-27 US disclosed
US-20240018175-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS AND ELECTRONIC EQUIPMENT INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-18 US disclosed
US-20240018175-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS AND ELECTRONIC EQUIPMENT INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-18 US disclosed
US-20230406808-A1 DEHYDRATION OF LACTIC ACID AND RELATED COMPOUNDS IN SOLID ACIDS VIA MULTIFUNCTIONAL FLEXIBLE MODIFIERS NATIONAL SCIENCE FOUNDATION 2023-12-21 US disclosed
US-20230329103-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-12 US disclosed
US-11744146-B2 Amine-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-29 US disclosed
EP-3675847-B1 SPIROCYCLE COMPOUNDS AND METHODS OF MAKING AND USING SAME H LUNDBECK AS (DK) 2023-07-12 EP disclosed
US-11696499-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-04 US disclosed
US-20040116399-A1 Inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. 2004-06-17 US disclosed
US-6720329-B2 ANTIINFLAMMATORY AGENTS BRISTOL-MYERS SQUIBB PHARMA 2004-04-13 US disclosed
EP-1373199-A4 SPIRO-CYCLIC BETA-AMINO ACID DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES AND TNF-ALPHA CONVERTING ENZYME (TAGE) BRISTOL MYERS SQUIBB PHARMA CO (US) 2004-04-07 EP disclosed
US-20040039013-A1 Process for preparing a substituted imidazopyridine compound ASTRAZENECA AB (SE) 2004-02-26 US disclosed
EP-1373199-A2 SPIRO-CYCLIC BETA-AMINO ACID DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES AND TNF-ALPHA CONVERTING ENZYME (TAGE) Bristol-Myers Squibb Pharma Company (US) 2004-01-02 EP disclosed
EP-1317455-A1 PROCESS FOR PREPARING A SUBSTITUTED IMIDAZOPYRIDINE COMPOUND AstraZeneca AB (SE) 2003-06-11 EP disclosed
WO-2002074738-A2 SPIRO-CYCLIC BETA-AMINO ACID DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES AND TNF-ALPHA CONVERTING ENZYME (TAGE) BRISTOL-MYERS SQUIBB COMPANY (US) 2002-09-26 WO disclosed
WO-2002020523-A1 PROCESS FOR PREPARING A SUBSTITUTED IMIDAZOPYRIDINE COMPOUND ASTRAZENECA AB (SE) 2002-03-14 WO disclosed
EP-0841904-A1 ORAL PHARMACEUTICAL COMPOSITIONS WITH DELAYED RELEASE OF REVERSIBLE PROTON PUMP INHIBITORS Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1998-05-20 EP disclosed
WO-1997002021-A1 ORAL PHARMACEUTICAL COMPOSITIONS WITH DELAYED RELEASE OF REVERSIBLE PROTON PUMP INHIBITORS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1997-01-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018175-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS AND ELECTRONIC EQUIPMENT INCLUDING THE LIGHT-EMITTING DEVICE GPX1, LAGE3, NFE2L2 KMT2A 119/4885KDM4E 913/4885ALDH1A1 17/4885
US-20040039013-A1 Process for preparing a substituted imidazopyridine compound CYP1B1, BRD1, SKP1 KMT2A 2103/4885KDM4E 1571/4885ALDH1A1 456/4885
US-20250243194-A1 ANTAGONIST OF ADENOSINE RECEPTORS ADORA2B, ADORA2A, ADORA1 KMT2A 2476/4885KDM4E 3478/4885ALDH1A1 637/4885
US-11744146-B2 Amine-based compound and organic light-emitting device including the same AOC2, AOC1, EML4 KMT2A 149/4885KDM4E 655/4885ALDH1A1 76/4885
US-20240208952-A1 THIOPHENE GLP-1 RECEPTOR AGONIST AND USE THEREOF GLP1R, GIPR, GCGR KMT2A 4321/4885KDM4E 2930/4885ALDH1A1 2375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.