Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8830192 | 0.85 | RXRA (0.53) | LMNAMAPTSMN1; SMN2HTTKAT2B | |
| SCHEMBL8830296 | 0.85 | KAT2B (0.46) | LMNAMAPTSMN1; SMN2HTTKAT2B | |
| SCHEMBL12329536 | 0.85 | MAPT (0.44) | LMNAMAPTSMN1; SMN2HTTCYP3A4 | |
| SCHEMBL8830299 | 0.84 | HPGD (0.46) | LMNAMAPTSMN1; SMN2HTTKAT2B | |
| SCHEMBL5913121 | 0.83 | POLB (0.42) | LMNAMAPTSMN1; SMN2HTTCYP3A4 | |
| SCHEMBL13634220 | 0.83 | ALDH1A1 (0.48) | LMNAMAPTSMN1; SMN2HTTKAT2B | |
| SCHEMBL27907999 | 0.79 | CES2 (0.52) | LMNAMAPTSMN1; SMN2HTTKAT2B | |
| SCHEMBL404538 | 0.78 | TSHR (0.58) | LMNAMAPTSMN1; SMN2HTTCYP3A4 | |
| SCHEMBL10959235 | 0.77 | TSHR (0.55) | LMNAMAPTSMN1; SMN2HTTKAT2B | |
| SCHEMBL11225857 | 0.76 | ALDH1A1 (0.51) | LMNAMAPTSMN1; SMN2HTTKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684049-A | HIV-inhibiting benzeneacetamide derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-11-04 | — | — | US | disclosed |
| EP-0538301-B1 | HIV-INHIBITING BENZENEACETAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 1996-10-30 | — | — | EP | disclosed |
| CN-1033142-C | A process for preparing pharmaceutical composition showing properties in against human immunodeficiency virus | JANSSEN PHARMACEUTICA NV (BE) | 1996-10-30 | — | — | CN | disclosed |
| US-5556886-A | VIRICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-09-17 | — | — | US | disclosed |
| CN-1107835-A | A process for preparing pharmaceutical composition showing properties in against human immunodeficiency virus | JANSSEN PHARMACEUTICA NV (BE) | 1995-09-06 | — | — | CN | disclosed |
| CN-1028990-C | Process for preparing phenylacetamide derivatives for inhibiting human immunodeficiency virus | JANSSEN PHARMACEUTICA NV (BE) | 1995-06-21 | — | — | CN | disclosed |
| EP-0538301-A1 | HIV-INHIBITING BENZENEACETAMIDE DERIVATIVES. | JANSSEN PHARMACEUTICA NV (BE) | 1993-04-28 | — | — | EP | disclosed |
| CN-1058958-A | HIV inhibiting phenylacetamide derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1992-02-26 | — | — | CN | disclosed |
| WO-1992000952-A1 | HIV-INHIBITING BENZENEACETAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-01-23 | — | — | WO | disclosed |