Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPD | P32754 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13497998 | 0.87 | MAPT (0.49) | KAT2BLMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL5913686 | 0.87 | MAPT (0.50) | ALDH1A1HPGDCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8830192 | 0.87 | RXRA (0.53) | KAT2BLMNAKMT2AALDH1A1HPGD | |
| SCHEMBL8830243 | 0.85 | LMNA (0.51) | KAT2BLMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL8830299 | 0.85 | HPGD (0.46) | KAT2BLMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL13634220 | 0.84 | ALDH1A1 (0.48) | KAT2BLMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL14081878 | 0.83 | HPGD (0.41) | LMNAKMT2AALDH1A1MEN1HPGD | |
| SCHEMBL27907999 | 0.80 | CES2 (0.52) | KAT2BLMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL2327753 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TDP1 | |
| SCHEMBL28822467 | 0.79 | LMNA (0.53) | LMNAKMT2AALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684049-A | HIV-inhibiting benzeneacetamide derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-11-04 | — | — | US | disclosed |
| EP-0538301-B1 | HIV-INHIBITING BENZENEACETAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 1996-10-30 | — | — | EP | disclosed |
| US-5556886-A | VIRICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-09-17 | — | — | US | disclosed |
| EP-0538301-A1 | HIV-INHIBITING BENZENEACETAMIDE DERIVATIVES. | JANSSEN PHARMACEUTICA NV (BE) | 1993-04-28 | — | — | EP | disclosed |
| WO-1992000952-A1 | HIV-INHIBITING BENZENEACETAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-01-23 | — | — | WO | disclosed |