SCHEMBL8830293

SCHEMBL8830293

CCCOc1nc(N)nc2[nH]cnc12

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 15/20 0.60
CCNB1 P14635 15/20 0.60
CDK2 P24941 14/20 0.60
CCNA2 P20248 13/20 0.60
CCNA1 P78396 13/20 0.60
PIN1 Q13526 1/20 0.51
NOS1 P29475 2/20 0.39
MGMT P16455 2/20 0.38
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL880169 0.92 CDK1 (0.61) CDK1CCNB1CDK2CCNA2CCNA1
SCHEMBL8618497 0.87 CDK1 (0.44) CDK1CCNB1CDK2CCNA2CCNA1
SCHEMBL8537496 0.86 CDK1 (0.44) CDK1CCNB1CDK2CCNA2CCNA1
SCHEMBL6925964 0.85 CDK1 (0.43) CDK1CCNB1CDK2CCNA2CCNA1
SCHEMBL12227596 0.84 CDK1 (0.42) CDK1CCNB1CDK2CCNA2CCNA1
SCHEMBL16357819 0.83 PIN1 (0.50) CDK1CCNB1CDK2CCNA2CCNA1
Methylguanine SCHEMBL1336757 0.80 CDK1 (0.41) CDK1CCNB1CDK2CCNA2CCNA1
Methylguanine SCHEMBL29968306 0.80 CDK1 (0.41) CDK1CCNB1CDK2CCNA2CCNA1
6-Chloroguanine SCHEMBL17187923 0.80 CDK1 (0.39) CDK1CCNB1CDK2CCNA2CCNA1
SCHEMBL821881 0.80 CDK1 (0.46) CDK1CCNB1CDK2CCNA2CCNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9145417-B2 Optical performance humidity dependency improving agent for cellulose acylate film FUJIFILM CORPORATION (JP) 2015-09-29 US disclosed
US-9145417-B2 Optical performance humidity dependency improving agent for cellulose acylate film FUJIFILM CORPORATION (JP) 2015-09-29 US disclosed
US-20110262661-A1 Optical performance humidity dependency improving agent for cellulose acylate film FUJIFILM CORPORATION (JP) 2011-10-27 US disclosed
US-20110262661-A1 Optical performance humidity dependency improving agent for cellulose acylate film FUJIFILM CORPORATION (JP) 2011-10-27 US disclosed
US-5637574-A VIRICIDES GLAXO WELLCOME INC. (US) 1997-06-10 US disclosed
EP-0417999-B1 Antiviral compounds WELLCOME FOUND (GB) 1996-03-13 EP disclosed
EP-0671410-A1 Antiviral compounds THE WELLCOME FOUNDATION LIMITED (GB) 1995-09-13 EP disclosed
US-5420115-A Method for the treatment of protoza infections with 21 -deoxy-21 -fluoropurine nucleosides BURROUGHS WELLCOME CO. (US) 1995-05-30 US disclosed
EP-0620734-A1 THERAPEUTIC NUCLEOSIDES THE WELLCOME FOUNDATION LIMITED (GB) 1994-10-26 EP disclosed
WO-1993013778-A1 THERAPEUTIC NUCLEOSIDES THE WELLCOME FOUNDATION LIMITED (GB) 1993-07-22 WO disclosed
US-5153318-A Viricides for hepatitis and human t-cell leukemia/lymphoma viruses BURROUGHS WELLCOME CO. (US) 1992-10-06 US disclosed
EP-0421739-A1 3'-azido purine nucleoside THE WELLCOME FOUNDATION LIMITED (GB) 1991-04-10 EP disclosed
EP-0417999-A1 Antiviral compounds THE WELLCOME FOUNDATION LIMITED (GB) 1991-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110262661-A1 Optical performance humidity dependency improving agent for cellulose acylate film ALKBH1, ACOT7, ALKBH2 CDK1 3407/4885CCNB1 2736/4885CDK2 3855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.