Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8830674 | 0.89 | PTGS1 (0.40) | ADORA2BALDH1A1PTGS1PTGS2 | |
| SCHEMBL8830647 | 0.88 | PTGS1 (0.39) | ADORA2BHPGDPTGS1PTGS2 | |
| SCHEMBL8830563 | 0.88 | PTGS1 (0.40) | ADORA2BKDM4EALDH1A1HPGDPTGS1 | |
| SCHEMBL8830571 | 0.85 | ADORA2B (0.56) | ADORA2BKDM4EHSD17B10 | |
| SCHEMBL8830905 | 0.81 | ALDH1A1 (0.41) | ADORA2BKDM4EALDH1A1HPGDGAA | |
| SCHEMBL8830751 | 0.75 | KMT2A (0.41) | ADORA2BKDM4EALDH1A1HPGDGAA | |
| SCHEMBL8830603 | 0.74 | KDM4E (0.41) | ADORA2BKDM4EALDH1A1HPGDGAA | |
| SCHEMBL8830678 | 0.73 | ADORA2A (0.47) | ADORA2BKDM4EHSD17B10 | |
| SCHEMBL8830649 | 0.73 | ADORA2A (0.47) | ADORA2BKDM4EHSD17B10 | |
| SCHEMBL8830564 | 0.72 | ADORA2B (0.53) | ADORA2BKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661153-A | FOR TREATING ALLERGIES, ASTHMA, DERMATITIS, GRAFT REJECTIONS | JAPAN ENERGY CORPORATION (JP) | 1997-08-26 | — | — | US | disclosed |
| EP-0700908-A1 | 1-Arylpyrimidine derivatives and pharmaceutical use thereof | JAPAN ENERGY CORPORATION (JP) | 1996-03-13 | — | — | EP | disclosed |