Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 4/20 | 0.51 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.51 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.51 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.51 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.51 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ACLY | P53396 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8831402 | 0.92 | PSEN1 (0.54) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL31609293 | 0.92 | PSEN1 (0.54) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8831768 | 0.91 | PSEN1 (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28837130 | 0.85 | FABP4 (0.51) | CNR2FABP4FABP5MAOAMAOB | |
| SCHEMBL351619 | 0.85 | FABP4 (0.58) | FABP4FABP5MAOAMAOB | |
| SCHEMBL30479089 | 0.85 | FABP4 (0.58) | FABP4FABP5MAOAMAOB | |
| SCHEMBL28952709 | 0.84 | FABP4 (0.50) | CNR2FABP4FABP5MAOAMAOB | |
| SCHEMBL25354476 | 0.84 | MAOA (0.59) | FABP4FABP5MAOAMAOB | |
| SCHEMBL4203950 | 0.84 | MAOA (0.59) | FABP4FABP5MAOAMAOB | |
| SCHEMBL1472359 | 0.84 | MAOA (0.59) | FABP4FABP5MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1050604-C | Compound with antipsychotic effect | MEIJI SEIKA KABUSHIKA KAISHA (JP) | 2000-03-22 | — | — | CN | disclosed |
| US-5599815-A | SIDE EFFECT REDUCTION | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-02-04 | — | — | US | disclosed |
| CN-1103534-A | Compound with antipsychotic effect | MEIJI SEIKA CO (JP) | 1995-06-07 | — | — | CN | disclosed |
| EP-0635506-A1 | COMPOUND WITH ANTIPSYCHOTIC EFFECT | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-01-25 | — | — | EP | disclosed |