Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TACR2 | P21452 | 3/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8831484 | 0.92 | LGALS3 (0.42) | LMNAPOLBKMT2AALDH1A1CYP2D6 | |
| SCHEMBL9332848 | 0.87 | LMNA (0.52) | LMNAPOLBKMT2AALDH1A1CYP2D6 | |
| SCHEMBL24804649 | 0.87 | LMNA (0.52) | LMNAPOLBKMT2AALDH1A1CYP2D6 | |
| SCHEMBL9332856 | 0.87 | LMNA (0.52) | LMNAPOLBKMT2AALDH1A1CYP2D6 | |
| SCHEMBL29865166 | 0.87 | LMNA (0.52) | LMNAPOLBKMT2AALDH1A1CYP2D6 | |
| SCHEMBL6553247 | 0.86 | TNF (0.42) | LMNAPOLBKMT2AALDH1A1CYP2D6 | |
| SCHEMBL6553250 | 0.86 | TNF (0.42) | LMNAPOLBKMT2AALDH1A1CYP2D6 | |
| SCHEMBL6553337 | 0.85 | CYP3A4 (0.41) | LMNAPOLBKMT2AALDH1A1CYP2D6 | |
| SCHEMBL6553329 | 0.85 | CYP3A4 (0.41) | LMNAPOLBKMT2AALDH1A1CYP2D6 | |
| SCHEMBL6553532 | 0.85 | TSHR (0.41) | LMNAPOLBKMT2AALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646123-A | Time dependent administration of oligosaccharide glycosides related to blood group determinants having a type I or type II core structure in reducing inflammation in a sensitized mammal arising form exposure to an antigen | ALBERTA RESEARCH COUNCIL (CA) | 1997-07-08 | — | — | US | disclosed |
| US-5580858-A | Immunosuppressive and tolerogenic modified Lewisx compounds | ALBERTA RESEARCH COUNCIL (CA) | 1996-12-03 | — | — | US | disclosed |
| WO-1993024505-A1 | REDUCING INFLAMMATION BY TIME DEPENDENT ADMINISTRATION OF OLIGOSACCHARIDES GLYCOSIDES RELATED TO BLOOD GROUP DETERMINANTS | ALBERTA RESEARCH COUNCIL (CA) | 1993-12-09 | — | — | WO | disclosed |