Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175239 | 0.86 | KCNN4 (0.48) | KCNN4KCNA3ALDH1A1MMP2CA1 | |
| SCHEMBL28857559 | 0.81 | KCNN4 (0.52) | KCNN4KCNA3ALDH1A1MMP2CA1 | |
| SCHEMBL28565985 | 0.73 | KCNN4 (0.60) | KCNN4KCNA3MMP2CA1CA2 | |
| SCHEMBL28448934 | 0.73 | KCNN4 (0.49) | KCNN4KCNA3ALDH1A1MMP2CA1 | |
| SCHEMBL28565008 | 0.72 | KCNN4 (0.59) | KCNN4KCNA3MMP2CA1CA2 | |
| SCHEMBL28556866 | 0.72 | KCNN4 (0.59) | KCNN4KCNA3MMP2CA1CA2 | |
| SCHEMBL2570325 | 0.68 | ALDH1A1 (0.52) | KCNN4KCNA3ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL2705838 | 0.66 | MEN1 (0.55) | KCNN4KCNA3ALDH1A1L3MBTL1GAA | |
| SCHEMBL8465404 | 0.66 | HTR6 (0.51) | KCNN4KCNA3ALDH1A1LMNAKMT2A | |
| SCHEMBL8673020 | 0.66 | KCNN4 (0.56) | KCNN4KCNA3ALDH1A1MMP2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544812-B1 | BISPHOSPHONIC ACID DERIVATIVES AS ANTI-ARTHRITIC AGENTS | UPJOHN CO (US) | 1995-04-05 | — | — | EP | claimed |
| US-5602115-A | Bisphosphonic acid derivatives as anti-arthritic agents | THE UPJOHN COMPANY (US) | 1997-02-11 | — | — | US | disclosed |