Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.41 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8465151 | 0.86 | MMP2 (0.43) | HTR6KMT2AALDH1A1MAPTCYP19A1 | |
| SCHEMBL8029313 | 0.83 | HTR6 (0.47) | HTR6SMN1; SMN2KMT2ALMNAALDH1A1 | |
| SCHEMBL25411625 | 0.77 | HTR6 (0.43) | HTR6SMN1; SMN2KMT2ALMNAALDH1A1 | |
| SCHEMBL25411629 | 0.77 | HTR6 (0.43) | HTR6SMN1; SMN2KMT2ALMNAALDH1A1 | |
| SCHEMBL25410726 | 0.74 | HTR6 (0.40) | HTR6SMN1; SMN2KMT2ALMNAALDH1A1 | |
| SCHEMBL25410730 | 0.74 | HTR6 (0.40) | HTR6SMN1; SMN2KMT2ALMNAALDH1A1 | |
| SCHEMBL25410650 | 0.72 | PKM (0.43) | HTR6KMT2ALMNAALDH1A1POLB | |
| SCHEMBL25410654 | 0.72 | PKM (0.43) | HTR6KMT2ALMNAALDH1A1POLB | |
| SCHEMBL29482649 | 0.72 | LMNA (0.51) | KMT2ALMNAALDH1A1KDM4EMAPT | |
| SCHEMBL28712877 | 0.72 | LMNA (0.51) | KMT2ALMNAALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998451-A | LIPOXYGENASE INHIBITORS | PFIZER INC (US) | 1999-12-07 | — | — | US | disclosed |
| US-5059609-A | Lipoxygenase inhibitors; leukotriene receptor blockers; psoriasis; antiulcer agents and myocardial infarctions | PFIZER INC. (US) | 1991-10-22 | — | — | US | disclosed |