Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8832537 | 0.86 | ECE1 (0.31) | SIGMAR1ECE1 | |
| SCHEMBL8833217 | 0.81 | ALDH1A1 (0.34) | SIGMAR1ECE1 | |
| SCHEMBL8834306 | 0.81 | SIGMAR1 (0.30) | SIGMAR1 | |
| SCHEMBL8832907 | 0.80 | SIGMAR1 (0.31) | SIGMAR1ECE1 | |
| SCHEMBL8832794 | 0.80 | SIGMAR1 (0.33) | SIGMAR1ECE1 | |
| SCHEMBL9213696 | 0.78 | ECE1 (0.34) | ECE1 | |
| SCHEMBL8833197 | 0.78 | ECE1 (0.34) | ECE1 | |
| SCHEMBL7805577 | 0.78 | ECE1 (0.33) | SIGMAR1ECE1 | |
| SCHEMBL9220659 | 0.78 | ECE1 (0.30) | ECE1 | |
| SCHEMBL9215991 | 0.77 | ECE1 (0.34) | SIGMAR1ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608056-A | Substituted 3-pyrrolidinylthio-carbapenems as antimicrobial agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| WO-1993021186-A1 | SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-28 | — | — | WO | disclosed |