SCHEMBL8833191

SCHEMBL8833191

CC(C=O)c1ccc(C(=O)NCc2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 4/20 0.59
HDAC2 Q92769 1/20 0.59
HDAC8 Q9BY41 1/20 0.59
RAB9A P51151 4/20 0.58
LMNA P02545 2/20 0.58
HPGD P15428 1/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
HDAC1 Q13547 3/20 0.55
KDM4E B2RXH2 1/20 0.55
POLB P06746 1/20 0.55
TSHR P16473 1/20 0.55
RECQL P46063 1/20 0.55
PPARG P37231 1/20 0.54
APOBEC3A P31941 1/20 0.54
CTDSP1 Q9GZU7 1/20 0.54
APOBEC3G Q9HC16 1/20 0.54
ROCK2 O75116 1/20 0.52
RPS6KA5 O75582 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL104431 0.85 RAB9A (0.75) HDAC6HDAC2HDAC8RAB9ALMNA
SCHEMBL8833182 0.82 HDAC6 (0.62) HDAC6HDAC2HDAC8RAB9ALMNA
SCHEMBL11900090 0.81 HDAC6 (0.85) HDAC6HDAC2HDAC8RAB9ALMNA
SCHEMBL10099556 0.79 RAB9A (0.75) HDAC6HDAC2HDAC8RAB9ALMNA
SCHEMBL457082 0.78 HDAC6 (0.79) HDAC6HDAC2HDAC8RAB9ALMNA
SCHEMBL2166139 0.77 EPHX2 (0.68) HDAC6HDAC2HDAC8RAB9ALMNA
SCHEMBL16589429 0.77 HDAC6 (0.72) HDAC6HDAC2HDAC8RAB9ALMNA
SCHEMBL178366 0.77 MAPK14 (0.75) HDAC6HDAC2HDAC8RAB9ALMNA
SCHEMBL6843720 0.76 HDAC6 (0.77) HDAC6HDAC2HDAC8RAB9ALMNA
SCHEMBL4747957 0.76 NR1H4 (0.81) HDAC6HDAC2HDAC8RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5629200-A MICROORGANISM DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1997-05-13 US disclosed