Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833251 | 0.96 | SMN1; SMN2 (0.35) | MAPK10SMN1; SMN2L3MBTL1CCNE1CDK2 | |
| SCHEMBL8833517 | 0.90 | CDK2 (0.33) | CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL8833248 | 0.84 | CCNE1 (0.36) | SMN1; SMN2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL8833774 | 0.79 | FDPS (0.35) | MAPK10SMN1; SMN2L3MBTL1NPC1GLA | |
| SCHEMBL8833145 | 0.78 | CDK2 (0.38) | MAPK10SMN1; SMN2L3MBTL1NPC1GLA | |
| SCHEMBL8833766 | 0.76 | CCNE1 (0.35) | SMN1; SMN2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL8833591 | 0.74 | SMN1; SMN2 (0.38) | MAPK10SMN1; SMN2CCNE1CDK2CDK5 | |
| SCHEMBL8832893 | 0.73 | FDPS (0.39) | MAPK10SMN1; SMN2L3MBTL1CCNE1CDK2 | |
| SCHEMBL8834125 | 0.68 | FDPS (0.37) | MAPK10SMN1; SMN2CCNE1CDK2CDK5 | |
| SCHEMBL8833783 | 0.62 | FDPS (0.41) | SMN1; SMN2L3MBTL1NPC1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654322-A | HYPOTENSIVE AGENTS, CEREBRAL APOPLEXY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0656355-A1 | BIPHENYLMETHANE DERIVATIVE AND MEDICINE CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-06-07 | — | — | EP | disclosed |