Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 5/20 | 0.35 |
| ▸ | CDK2 | P24941 | 5/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833649 | 0.79 | CCNE1 (0.38) | CCNE1CDK2CDK5CDK5R1SMN1; SMN2 | |
| SCHEMBL8833522 | 0.76 | NAAA (0.33) | CCNE1CDK2CDK5CDK5R1SMN1; SMN2 | |
| SCHEMBL16266936 | 0.74 | ALDH1A1 (0.39) | CCNE1CDK2CDK5CDK5R1SMN1; SMN2 | |
| SCHEMBL8833079 | 0.70 | FDPS (0.40) | CCNE1CDK2CDK5SMN1; SMN2 | |
| SCHEMBL28112274 | 0.67 | CCNE1 (0.37) | CCNE1CDK2CDK5CDK5R1SMN1; SMN2 | |
| SCHEMBL17484176 | 0.66 | CCR2 (0.34) | CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL20883053 | 0.62 | CCNE1 (0.60) | CCNE1CDK2CDK5CDK5R1SMN1; SMN2 | |
| SCHEMBL21092429 | 0.61 | — | — | |
| SCHEMBL27259607 | 0.61 | ALDH1A1 (0.41) | CCNE1CDK2CDK5SMN1; SMN2 | |
| SCHEMBL24572410 | 0.61 | CCNE1 (0.49) | CCNE1CDK2CDK5CDK5R1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654322-A | HYPOTENSIVE AGENTS, CEREBRAL APOPLEXY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0656355-A1 | BIPHENYLMETHANE DERIVATIVE AND MEDICINE CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-06-07 | — | — | EP | disclosed |