Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3569653 | 0.83 | ALDH1A1 (0.40) | ALDH1A1NPSR1GLO1LMNAHSD17B10 | |
| SCHEMBL27631184 | 0.80 | ALDH1A1 (0.42) | ALDH1A1NPSR1LMNAHSD17B10TSHR | |
| SCHEMBL8149342 | 0.80 | ALDH1A1 (0.42) | ALDH1A1NPSR1LMNAHSD17B10TSHR | |
| SCHEMBL2458296 | 0.78 | ALDH1A1 (0.43) | ALDH1A1NPSR1GLO1LMNAHSD17B10 | |
| SCHEMBL3817055 | 0.78 | MGAM (0.43) | ALDH1A1NPSR1GLO1LMNAHSD17B10 | |
| SCHEMBL31491172 | 0.77 | ALDH1A1 (0.42) | ALDH1A1NPSR1GLO1LMNAHSD17B10 | |
| SCHEMBL28032709 | 0.76 | ALDH1A1 (0.42) | ALDH1A1NPSR1GLO1LMNAHSD17B10 | |
| SCHEMBL4773196 | 0.75 | TDP1 (0.38) | ALDH1A1NPSR1GLO1LMNAHSD17B10 | |
| SCHEMBL3828447 | 0.75 | ZDHHC7 (0.40) | ALDH1A1NPSR1GLO1LMNAHSD17B10 | |
| SCHEMBL27940805 | 0.75 | ALOX15 (0.39) | ALDH1A1NPSR1GLO1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654322-A | HYPOTENSIVE AGENTS, CEREBRAL APOPLEXY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0656355-A1 | BIPHENYLMETHANE DERIVATIVE AND MEDICINE CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-06-07 | — | — | EP | disclosed |
| US-5378803-A | Analgesics, substance P antagonists, peptides containing thiazole, oxazole or imidazole ring and indole ring | STERLING WINTHROP INC. (US) | 1995-01-03 | — | — | US | disclosed |