SCHEMBL883499

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9109611	0.86	TTR (0.43)	EPAS1TTRL3MBTL1NPSR1MAPT
	SCHEMBL875278	0.86	EPAS1 (0.55)	EPAS1TTRARL3MBTL1NPSR1
	SCHEMBL875557	0.86	EPAS1 (0.52)	EPAS1TTRARL3MBTL1NPSR1
	SCHEMBL3900976	0.85	TTR (0.64)	TTRARNR1H2NR1H3
	SCHEMBL875580	0.85	FFAR1 (0.51)	EPAS1TTR
	SCHEMBL876331	0.85	EPAS1 (0.48)	EPAS1TTRARL3MBTL1NPSR1
	SCHEMBL9889486	0.85	AR (0.48)	EPAS1TTRARL3MBTL1ALDH1A1
	SCHEMBL15278007	0.84	EPAS1 (0.47)	EPAS1TTRARL3MBTL1NPSR1
	SCHEMBL875489	0.84	AR (0.53)	EPAS1TTRARL3MBTL1NPSR1
	SCHEMBL11195440	0.82	PRKCA (0.50)	EPAS1L3MBTL1SMN1; SMN2PRKCAPRKCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.