Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11228644 | 0.81 | NOS1 (0.39) | NOS1TLR8DNM1TBXAS1 | |
| SCHEMBL5614512 | 0.76 | NOS1 (0.42) | NOS1TLR8 | |
| SCHEMBL14059429 | 0.71 | NOS1 (0.34) | NOS1 | |
| SCHEMBL3920608 | 0.66 | NOS1 (0.39) | NOS1 | |
| SCHEMBL45207 | 0.65 | TLR8 (0.44) | NOS1TLR8TBXAS1 | |
| Methylamine SCHEMBL27939089 | 0.64 | TLR8 (0.48) | NOS1TLR8TBXAS1 | |
| SCHEMBL8511793 | 0.64 | NOS1 (0.38) | NOS1 | |
| SCHEMBL11440961 | 0.63 | TBXAS1 (0.47) | NOS1TLR8TBXAS1 | |
| SCHEMBL6114640 | 0.63 | TBXAS1 (0.47) | NOS1TLR8TBXAS1 | |
| SCHEMBL6114991 | 0.63 | TBXAS1 (0.47) | NOS1TLR8TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9316078-A | — | — | None | — | — | JP | disclosed |
| JP-H09316078-A | PRODUCTION OF ACYLHYDRAZINOPYRAZOLE DERIVATIVE AND PYRAZOLE (5,1-C)-1,2,4-TRIAZOLE COMPOUND | EASTMAN KODAK CO | 1997-12-09 | — | — | JP | disclosed |
| EP-0212353-A2 | 1-Aryl-5-hydrazino-pyrazoles | BAYER AG (DE) | 1987-03-04 | — | — | EP | disclosed |