SCHEMBL11228644

SCHEMBL11228644

CCCCCN(CCCCC)n1cccn1

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 3/20 0.39
DNM1 Q05193 3/20 0.32
TBXAS1 P24557 1/20 0.32
TLR8 Q9NR97 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14059429 0.86 NOS1 (0.34) NOS1
SCHEMBL8835357 0.81 NOS1 (0.41) NOS1DNM1TBXAS1TLR8
SCHEMBL5614512 0.75 NOS1 (0.42) NOS1TLR8
SCHEMBL45207 0.67 TLR8 (0.44) NOS1TBXAS1TLR8
SCHEMBL28875541 0.67 DNM1 (0.42) DNM1TBXAS1
SCHEMBL5691507 0.65 TBXAS1 (0.47) NOS1TBXAS1TLR8
SCHEMBL6114991 0.65 TBXAS1 (0.47) NOS1TBXAS1TLR8
SCHEMBL6114927 0.65 TBXAS1 (0.47) NOS1TBXAS1TLR8
SCHEMBL6114716 0.65 TBXAS1 (0.47) NOS1TBXAS1TLR8
SCHEMBL11440961 0.65 TBXAS1 (0.47) NOS1TBXAS1TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0046271-B1 PHOTOSENSITIVE COMPOSITIONS AND ELEMENTS CONTAINING SUBSTITUTED HYDROXYLAMINE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-10-19 EP disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
EP-0046271-A1 Photosensitive compositions and elements containing substituted hydroxylamine E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-02-24 EP disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4298678-A PHOTOOXIDANT AND LEUCO DYE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-11-03 US disclosed