SCHEMBL8835491

SCHEMBL8835491

C=C/C=C\CC1CCC(c2ccc(-c3cc(F)c(OC(F)(F)F)c(F)c3)cc2)CC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8835171 0.90 DGAT1 (0.31) FFAR4
SCHEMBL8835068 0.89
SCHEMBL8835381 0.88 CTSK (0.36)
SCHEMBL8835301 0.88 DGAT1 (0.33)
SCHEMBL8835294 0.85
SCHEMBL8835312 0.85 L3MBTL1 (0.40) L3MBTL1
SCHEMBL8453291 0.83 ESR1 (0.33) FFAR4
SCHEMBL8453292 0.83 ESR1 (0.33) FFAR4
SCHEMBL8453303 0.83 ESR1 (0.33) FFAR4
SCHEMBL8453298 0.83 ESR1 (0.33) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5662830-A Diene derivative CHISSO CORPORATION (JP) 1997-09-02 US disclosed
US-5609791-A Diene derivative CHISSO CORPORATION (JP) 1997-03-11 US disclosed
EP-0563982-B1 Polycyclic diene derivatives CHISSO CORP (JP) 1996-07-17 EP disclosed
US-5449810-A Diene derivative CHISSO CORPORATION (JP) 1995-09-12 US disclosed
EP-0563982-A2 Polycyclic diene derivatives Chisso Corporation (JP) 1993-10-06 EP disclosed