Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 2/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835320 | 0.91 | EPHX2 (0.33) | CTSKNAAAEPHX2PDE2ACHRM2 | |
| SCHEMBL8835143 | 0.91 | CTSK (0.36) | CTSKNAAAS1PR1EPHX2GRM2 | |
| SCHEMBL8835491 | 0.88 | FFAR4 (0.31) | — | |
| SCHEMBL8447952 | 0.87 | CTSK (0.37) | CTSKNAAAS1PR1EPHX2GRM2 | |
| SCHEMBL8835301 | 0.84 | DGAT1 (0.33) | — | |
| SCHEMBL8835312 | 0.84 | L3MBTL1 (0.40) | EPHX2GRM2CHRM2CHRM1 | |
| SCHEMBL8835613 | 0.84 | KIF11 (0.41) | — | |
| SCHEMBL8835051 | 0.81 | EPHX2 (0.35) | EPHX2PDE2ACHRM2CHRM1 | |
| SCHEMBL23666165 | 0.81 | CTSK (0.38) | CTSKNAAAS1PR1EPHX2GRM2 | |
| SCHEMBL9062319 | 0.81 | CTSK (0.40) | CTSKNAAAS1PR1EPHX2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5662830-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5609791-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0563982-B1 | Polycyclic diene derivatives | CHISSO CORP (JP) | 1996-07-17 | — | — | EP | disclosed |
| US-5449810-A | Diene derivative | CHISSO CORPORATION (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0563982-A2 | Polycyclic diene derivatives | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |