⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17027475 | 1.00 | — | — | |
| SCHEMBL14240273 | 0.82 | SHBG (0.32) | — | |
| SCHEMBL22869242 | 0.82 | SHBG (0.32) | — | |
| SCHEMBL2074977 | 0.75 | MAPK1 (0.35) | — | |
| SCHEMBL2074979 | 0.75 | MAPK1 (0.35) | — | |
| SCHEMBL12777784 | 0.69 | — | — | |
| Ethylene SCHEMBL7716211 | 0.69 | MAPK1 (0.32) | — | |
| Ethylene SCHEMBL8300809 | 0.69 | MAPK1 (0.32) | — | |
| SCHEMBL8349202 | 0.69 | — | — | |
| SCHEMBL4515462 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232057-B | Synthesis method of gliclazide intermediate 3-azabicyclo [3.3.0] octane | 上海巽田科技股份有限公司 | 2024-01-26 | — | — | CN | claimed |
| EP-4735447-A1 | AROMATIC NITROGEN-CONTAINING COMPOUNDS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025087274-A1 | AZABICYCLO DERIVATIVE AND PREPARATION METHOD THEREFOR, AND USE | 浙江海正药业股份有限公司 | 2025-05-01 | — | — | WO | disclosed |
| WO-2025002413-A1 | AROMATIC NITROGEN-CONTAINING COMPOUNDS, PREPARATION METHODS AND MEDICINAL USES THEREOF | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2025-01-02 | — | — | WO | disclosed |
| WO-2024255765-A1 | NOVEL COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF | NUPHASE THERAPEUTICS (HANGZHOU) LIMITED., CO. (CN) | 2024-12-19 | — | — | WO | disclosed |
| CN-115232057-B | Synthesis method of gliclazide intermediate 3-azabicyclo [3.3.0] octane | 上海巽田科技股份有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-115232057-B | Synthesis method of gliclazide intermediate 3-azabicyclo [3.3.0] octane | 上海巽田科技股份有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-115232057-A | Synthesis method of gliclazide intermediate 3-azabicyclo [3.3.0] octane | 上海巽田科技股份有限公司 | 2022-10-25 | — | — | CN | disclosed |
| US-5641784-A | ADENOSINE ANTAGONISTS; TREATMENT OF NERVOUS SYSTEM DISORDERS, ALZHEIMER'S DISEASE | BOEHRINGER INGELHEIM KG (DE) | 1997-06-24 | — | — | US | disclosed |
| EP-0487673-A1 | NEW XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) | 1992-06-03 | — | — | EP | disclosed |
| WO-1992000297-A1 | NEW XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM KG (DE) | 1992-01-09 | — | — | WO | disclosed |