Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1856518 | 0.81 | ALDH1A1 (0.45) | ALDH1A1TP53CYP3A4 | |
| SCHEMBL10348413 | 0.78 | ALDH1A1 (0.38) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL10348403 | 0.77 | ALDH1A1 (0.37) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL324023 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL4647897 | 0.74 | ALDH1A1 (0.56) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL30451 | 0.71 | THRB (0.44) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL433986 | 0.71 | ALDH1A1 (0.36) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL2404660 | 0.70 | ALDH1A1 (0.73) | ALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL11684738 | 0.70 | ALDH1A1 (0.73) | ALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL15049529 | 0.70 | ALDH1A1 (0.34) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608021-A | AMINO SUBSTITUTED (METH)ACRYLIC MONOMER, VINYL MONOMER, (METH)ACRYLOYL MONOMER, CROSSLINKABLE VINYL MONOMER | OSAKA YUKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0262488-B1 | REACTIVE ORGANIC FILLER AND ITS USE | Ivoclar AG (LI) | 1990-06-06 | — | — | EP | disclosed |
| EP-0262488-A1 | Reactive organic filler and its use | Ivoclar AG (LI) | 1988-04-06 | — | — | EP | disclosed |