Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 10/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CDK9 | P50750 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586701 | 0.85 | PKM (0.57) | FPR2EPHX2TSHRSMN1; SMN2ROCK2 | |
| SCHEMBL4068332 | 0.83 | HSD17B10 (0.56) | FPR2EPHX2TP53EPHX1TSHR | |
| SCHEMBL11580858 | 0.81 | NPC1 (0.77) | FPR2EPHX2SMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL6381444 | 0.81 | FPR2 (0.81) | FPR2MEN1KMT2A | |
| SCHEMBL6375751 | 0.81 | FPR2 (0.81) | FPR2MEN1KMT2A | |
| SCHEMBL6375756 | 0.81 | FPR2 (0.81) | FPR2MEN1KMT2A | |
| SCHEMBL8837452 | 0.81 | NPC1 (0.56) | NPC1RAB9A | |
| SCHEMBL8957524 | 0.79 | ROCK2 (0.56) | FPR2HSD17B10ROCK2ROCK1NPC1 | |
| SCHEMBL20611567 | 0.79 | FPR2 (0.63) | FPR2 | |
| SCHEMBL29686493 | 0.79 | FPR2 (0.63) | FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674864-A | ANALGESICS; ENDOPEPTIDASE AND ENKEPHALINASE INHIBITORS; CARDIOTONIC, PSYCHOTROPIC AND HYPERTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1997-10-07 | — | — | US | disclosed |
| US-5190974-A | Analgesics | ROUSSEL UCLAF (FR) | 1993-03-02 | — | — | US | disclosed |