Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRF | P10586 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
| ▸ | SCN1A | P35498 | 2/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8837565 | 0.80 | PTPN2 (0.42) | PTPRFPTPN2PTPN1HTR3AALDH1A1 | |
| SCHEMBL8837627 | 0.80 | CA1 (0.56) | PTPRFPTPN2PTPN1HTR3AALDH1A1 | |
| SCHEMBL6228820 | 0.76 | CA1 (0.59) | ALDH1A1KDM4EPOLBTSHRHSD17B10 | |
| SCHEMBL30806173 | 0.73 | TSHR (0.56) | ALDH1A1KDM4ETSHRHSD17B10CA1 | |
| SCHEMBL6226409 | 0.73 | NPC1 (0.47) | ALDH1A1KDM4EPOLBHSD17B10CA1 | |
| SCHEMBL9188413 | 0.73 | TSHR (0.56) | ALDH1A1KDM4ETSHRHSD17B10CA1 | |
| SCHEMBL9524237 | 0.73 | F2 (0.60) | ALDH1A1KDM4EPOLBTSHRCA1 | |
| SCHEMBL9025271 | 0.72 | PTPRF (0.36) | PTPRFPTPN2PTPN1HTR3AALDH1A1 | |
| SCHEMBL11334652 | 0.71 | CA1 (0.39) | ALDH1A1POLBTSHRCA1CA2 | |
| SCHEMBL11111735 | 0.71 | ALDH1A1 (0.58) | ALDH1A1KDM4EPOLBTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003980-A1 | SUBSTITUTED ARYL SULPHONYL AMINO (THIO) CARBONYL TRIAZOLIN(THI)ONES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-06 | — | — | WO | disclosed |