SCHEMBL9026170

SCHEMBL9026170

O=C(OC1COC1)c1ccccc1OS(=O)(=O)Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN1A P35498 3/20 0.40
SCN2A Q99250 3/20 0.40
SCN3A Q9NY46 3/20 0.40
PTPRF P10586 1/20 0.40
PTPN2 P17706 1/20 0.40
PTPN1 P18031 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MAPT P10636 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HTR3A P46098 7/20 0.38
POLB P06746 2/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
KAT2B Q92831 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9706667 0.83 ALDH1A1 (0.57) SCN1ASCN2ASCN3APTPRFPTPN2
SCHEMBL8837565 0.80 PTPN2 (0.42) SCN1ASCN2ASCN3APTPRFPTPN2
SCHEMBL9432849 0.79 HTR3A (0.37) PTPRFPTPN2PTPN1L3MBTL1HTR3A
SCHEMBL9706642 0.77 L3MBTL1 (0.39) SCN1ASCN2ASCN3APTPRFPTPN2
SCHEMBL9432860 0.77 KMT2A (0.35) PTPRFPTPN2PTPN1L3MBTL1MAPT
SCHEMBL8837627 0.74 CA1 (0.56) PTPRFPTPN2PTPN1HTR3APOLB
SCHEMBL9432844 0.73 PTPN2 (0.39) PTPRFPTPN2PTPN1HTR3APOLB
SCHEMBL8900371 0.72 POLB (0.46) SCN1ASCN2ASCN3APTPRFPTPN2
SCHEMBL8888943 0.69 PTPRF (0.38) SCN1ASCN2ASCN3APTPRFPTPN2
SCHEMBL28339381 0.69 CHRNA7 (0.56) SCN1ASCN2ASCN3APTPRFPTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0496701-B1 Sulfonylureas as herbizides CIBA GEIGY AG (CH) 1996-03-06 EP disclosed
EP-0480871-B1 Synergistic agents and method for selective control of weeds CIBA GEIGY AG (CH) 1995-12-13 EP disclosed
US-5310722-A Synergistic composition comprising a sulfonylurea and a thiadiazolo[3,4-a]py CIBA-GEIGY CORPORATION (US) 1994-05-10 US disclosed
EP-0496701-A1 Sulfonylureas as herbizides CIBA-GEIGY AG (CH) 1992-07-29 EP disclosed
EP-0480871-A2 Synergistic agents and method for selective control of weeds CIBA-GEIGY AG (CH) 1992-04-15 EP disclosed