Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7003660 | 0.81 | TUBB4A (0.52) | ALDH1A1GAAMAPTKMT2AL3MBTL1 | |
| Triacetoxyanthrene SCHEMBL9119527 | 0.80 | ALDH1A1 (0.65) | ALDH1A1GAAMAPTKMT2AL3MBTL1 | |
| SCHEMBL8837593 | 0.79 | GAA (0.57) | ALDH1A1GAAMAPTKMT2AL3MBTL1 | |
| SCHEMBL7004530 | 0.78 | HTT (0.40) | ALDH1A1GAAMAPTKDM4EPOLB | |
| SCHEMBL6993194 | 0.77 | TUBB4A (0.37) | GAAMAPTKDM4ETMIGD3HTT | |
| SCHEMBL5742360 | 0.75 | MAPK1 (0.44) | ALDH1A1GAAMAPTKMT2AL3MBTL1 | |
| SCHEMBL2680702 | 0.71 | ALDH1A1 (0.55) | ALDH1A1GAAMAPTKMT2AL3MBTL1 | |
| SCHEMBL8219437 | 0.71 | KDM4E (0.56) | ALDH1A1GAAMAPTKMT2AL3MBTL1 | |
| SCHEMBL15495626 | 0.70 | ADORA2A (0.47) | ALDH1A1GAAMAPTKMT2AL3MBTL1 | |
| SCHEMBL8148551 | 0.70 | KDM4E (0.34) | ALDH1A1GAAMAPTKDM4ETMIGD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060142271-A1 | Novel lapacho compounds and methods of use thereof | MUNSTER, UNIVERSITY OF (DE) | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142271-A1 | Novel lapacho compounds and methods of use thereof | XIAP, PIN1, NQO1 | ALDH1A1 1710/4885GAA 1179/4885MAPT 3494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.