SCHEMBL10206196

SCHEMBL10206196

Cc1ccc2c3ccc4c(c5ccccc5n4-c4ccccc4)c3n(-c3ccccc3)c2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
ATM Q13315 1/20 0.50
FGFR1 P11362 1/20 0.35
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 2/20 0.35
TSHR P16473 2/20 0.35
KMT2A Q03164 2/20 0.35
HSD17B10 Q99714 2/20 0.35
JAK2 O60674 1/20 0.35
JAK3 P52333 1/20 0.35
POLB P06746 1/20 0.35
BRCA1 P38398 1/20 0.35
RXFP1 Q9HBX9 2/20 0.35
GAA P10253 1/20 0.35
GFER P55789 1/20 0.35
LMNA P02545 2/20 0.34
HTT P42858 2/20 0.34
HPGD P15428 2/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10206157 1.00 KDM4E (0.50) KDM4EL3MBTL1ATMFGFR1ALDH1A1
SCHEMBL20412007 0.97 KDM4E (0.47) KDM4EL3MBTL1ATMFGFR1ALDH1A1
SCHEMBL15625284 0.96 KDM4E (0.46) KDM4EL3MBTL1ATMFGFR1ALDH1A1
SCHEMBL20412017 0.96 KDM4E (0.42) KDM4EL3MBTL1ATMFGFR1ALDH1A1
SCHEMBL20412015 0.93 KDM4E (0.40) KDM4EL3MBTL1ATMFGFR1ALDH1A1
SCHEMBL15451805 0.93 KDM4E (0.51) KDM4EL3MBTL1ATMFGFR1ALDH1A1
SCHEMBL10206223 0.93 KDM4E (0.47) KDM4EL3MBTL1ATMFGFR1ALDH1A1
SCHEMBL15625287 0.93 L3MBTL1 (0.43) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL14315736 0.92 KDM4E (0.53) KDM4EL3MBTL1ATMALDH1A1JAK2
SCHEMBL15451807 0.92 KDM4E (0.53) KDM4EL3MBTL1ATMALDH1A1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230122208-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-20 US disclosed
US-11548905-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-01-10 US disclosed
US-10454042-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2019-10-22 US disclosed
US-20160079545-A1 Organic Electroluminescence Device UDC Ireland (IE) 2016-03-17 US disclosed
US-9287515-B2 Compositions comprising organic and organometallic compounds, and their applications in organic electroluminescence, light emission, display, and illumination devices UDC Ireland (IE) 2016-03-15 US disclosed
US-20120153272-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20120153272-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230122208-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ZYX, SLC39A3, SOD3 KDM4E 1688/4885L3MBTL1 155/4885ATM 3316/4885
US-11548905-B2 Organic electroluminescent materials and devices ZYX, SLC39A3, SOD3 KDM4E 1688/4885L3MBTL1 155/4885ATM 3316/4885
US-10454042-B2 Organic electroluminescence device EML4, ELOC, ORC3 KDM4E 1789/4885L3MBTL1 770/4885ATM 2891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.