SCHEMBL8840477

SCHEMBL8840477

CCC(C)[C@H]1CC[C@@H](N)CC1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SHBG P04278 2/20 0.34
SMYD3 Q9H7B4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25935950 1.00 SHBG (0.34) SHBGSMYD3
SCHEMBL2404767 1.00 SHBG (0.34) SHBGSMYD3
SCHEMBL8840566 1.00 SHBG (0.34) SHBGSMYD3
SCHEMBL8675545 0.87 SHBG (0.42) SHBG
SCHEMBL1193150 0.87
SCHEMBL521520 0.86 SMYD3 (0.45) SHBGSMYD3
SCHEMBL23912364 0.86 SHBG (0.32) SHBG
SCHEMBL10292125 0.81 SMYD3 (0.33) SMYD3
SCHEMBL2409982 0.81 SMYD3 (0.33) SMYD3
SCHEMBL12507920 0.81 SMYD3 (0.30) SMYD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240425445-A1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & CO (US) 2024-12-26 US disclosed
US-12084401-B2 Trisamide compounds and compositions comprising the same MILLIKEN & COMPANY (US) 2024-09-10 US disclosed
EP-4073164-B1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & CO (US) 2024-05-22 EP disclosed
CN-117756662-A Triamide compound and composition comprising same 美利肯公司 2024-03-26 CN disclosed
EP-4332088-A2 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME Milliken & Company (US) 2024-03-06 EP disclosed
CN-115066462-B Triamide compound and composition comprising same 美利肯公司 2024-01-09 CN disclosed
US-20230312460-A1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & COMPANY 2023-10-05 US disclosed
US-11685732-B2 MYST family histone acetyltransferase inhibitors Epizyme, Inc. (US) 2023-06-27 US disclosed
US-11667603-B2 Trisamide compounds and compositions comprising the same MILLIKEN & COMPANY (US) 2023-06-06 US disclosed
EP-4073164-A1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME Milliken & Company (US) 2022-10-19 EP disclosed
CN-115066462-A Triamide compounds and compositions comprising the same 美利肯公司 2022-09-16 CN disclosed
US-20210179544-A1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & COMPANY 2021-06-17 US disclosed
WO-2021119632-A1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & COMPANY (US) 2021-06-17 WO disclosed
US-5650417-A Substituted pyridines, their preparation, and their use as pesticides and fungicides HOECHST SCHERING AGREVO GMBH (DE) 1997-07-22 US disclosed
EP-0719255-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES Hoechst Schering AgrEvo GmbH (DE) 1996-07-03 EP disclosed
WO-1995007890-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES HOECHST SCHERING AGREVO GMBH (DE) 1995-03-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667603-B2 Trisamide compounds and compositions comprising the same PTAR1, TIPRL, TCOF1 SHBG 4534/4885SMYD3 1743/4885
US-12084401-B2 Trisamide compounds and compositions comprising the same PTAR1, TIPRL, TCOF1 SHBG 4534/4885SMYD3 1743/4885
US-20240425445-A1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME PTAR1, TIPRL, TCOF1 SHBG 4534/4885SMYD3 1743/4885
US-20230312460-A1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME PTAR1, TIPRL, TCOF1 SHBG 4534/4885SMYD3 1743/4885
US-20210179544-A1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME PTAR1, TIPRL, TCOF1 SHBG 4534/4885SMYD3 1743/4885
US-11685732-B2 MYST family histone acetyltransferase inhibitors EP300, KAT2A, KAT6A SHBG 4301/4885SMYD3 191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.