Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29682049 | 1.00 | ALDH1A1 (0.34) | ALDH1A1KDM4EHSD17B10HTR1AHTR1D | |
| SCHEMBL3170691 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10MAOARAB9A | |
| SCHEMBL8710507 | 0.83 | TAS1R3 (0.36) | ALDH1A1KDM4EHSD17B10MAOARAB9A | |
| SCHEMBL30557385 | 0.83 | ALDH1A1 (0.35) | ALDH1A1KDM4EHSD17B10HTR1AHTR1D | |
| SCHEMBL1178052 | 0.83 | ALDH1A1 (0.35) | ALDH1A1KDM4EHSD17B10HTR1AHTR1D | |
| SCHEMBL25384445 | 0.81 | LOX (0.41) | ALDH1A1KDM4EHSD17B10HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL3180076 | 0.81 | MAOA (0.36) | ALDH1A1KDM4EHSD17B10MAOARAB9A | |
| Hydrochloric Acid SCHEMBL5268510 | 0.81 | ALDH1A1 (0.38) | ALDH1A1KDM4EHSD17B10MAOARAB9A | |
| SCHEMBL8840465 | 0.81 | ALDH1A1 (0.34) | ALDH1A1KDM4EHSD17B10MAOARAB9A | |
| SCHEMBL12601967 | 0.80 | PDE3B (0.37) | ALDH1A1KDM4EHSD17B10HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12590090-B2 | Pyrimidine-and nitrogen-containing bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2026-03-31 | — | — | US | disclosed |
| EP-4223750-B1 | NITROGEN-CONTAINING BICYCLIC COMPOUNDS WHICH CONTAIN PYRIMIDINE AS INTERLEUKIN 1 RECEPTOR-ASSOCIATED KINASE 4 (IRAK-4) INHIBITORS TO BE USED IN THE TREATMENT OF INFLAMMATORY OR AUTOIMMUNE DISEASES | ASAHI KASEI PHARMA CORP (JP) | 2025-06-25 | — | — | EP | disclosed |
| US-20240025893-A1 | PYRIMIDINE-AND NITROGEN-CONTAINING BICYCLIC COMPOUND | ASAHI KASEI PHARMA CORPORATION (JP) | 2024-01-25 | — | — | US | disclosed |
| US-20240025893-A1 | PYRIMIDINE-AND NITROGEN-CONTAINING BICYCLIC COMPOUND | ASAHI KASEI PHARMA CORPORATION (JP) | 2024-01-25 | — | — | US | disclosed |
| US-20240025893-A1 | PYRIMIDINE-AND NITROGEN-CONTAINING BICYCLIC COMPOUND | ASAHI KASEI PHARMA CORPORATION (JP) | 2024-01-25 | — | — | US | disclosed |
| EP-4223750-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND WHICH CONTAINS PYRIMIDINE | Asahi Kasei Pharma Corporation (JP) | 2023-08-09 | — | — | EP | disclosed |
| EP-4223750-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND WHICH CONTAINS PYRIMIDINE | Asahi Kasei Pharma Corporation (JP) | 2023-08-09 | — | — | EP | disclosed |
| CN-116194454-A | Pyrimidine-containing nitrogen-containing bicyclic compounds | 旭化成制药株式会社 | 2023-05-30 | — | — | CN | disclosed |
| US-20030171587-A1 | Antimicrobial 2-pyridones, their compositions and uses | THE PROCTER & GAMBLE COMPANY | 2003-09-11 | — | — | US | disclosed |
| EP-1341787-A2 | ANTIMICROBIAL 2-PYRIDONES, THEIR COMPOSITIONS AND USES | The Procter & Gamble Company (US) | 2003-09-10 | — | — | EP | disclosed |
| US-6509349-B1 | suppressing the growth or reproduction of microorganisms, such as bacteria. For example, such antibacterials and other antimicrobials are described in Antibiotics, Chemotherapeutics, and Antibacterial Agents for Disease | THE PROCTER & GAMBLE COMPANY | 2003-01-21 | — | — | US | disclosed |
| WO-2002048143-A2 | ANTIMICROBIAL 2-PYRIDONES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2002-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171587-A1 | Antimicrobial 2-pyridones, their compositions and uses | PIR, PRDX6, CLPP | ALDH1A1 3730/4885KDM4E 4436/4885HSD17B10 2583/4885 |
| US-20240025893-A1 | PYRIMIDINE-AND NITROGEN-CONTAINING BICYCLIC COMPOUND | IRAK4, IRAK1, IRAK2 | ALDH1A1 2898/4885KDM4E 624/4885HSD17B10 4158/4885 |
| US-12590090-B2 | Pyrimidine-and nitrogen-containing bicyclic compound | IRAK1, IRAK4, IRAK2 | ALDH1A1 3202/4885KDM4E 1029/4885HSD17B10 2801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.