SCHEMBL8840422

SCHEMBL8840422

COCc1nccc(N(OCc2ccccc2)C2(c3ccccc3)CCCCC2)c1OC

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 7/20 0.34
OPRL1 P41146 7/20 0.34
SLC6A5 Q9Y345 3/20 0.32
OPRK1 P41145 2/20 0.31
OPRD1 P41143 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9035779 0.92 OPRM1 (0.34) OPRM1OPRL1SLC6A5OPRK1
SCHEMBL8840459 0.92 OPRM1 (0.32) OPRM1OPRL1OPRK1OPRD1
SCHEMBL8840404 0.90 TSHR (0.36) OPRM1OPRL1
SCHEMBL8840544 0.90 MEN1 (0.36) OPRM1OPRL1SLC6A5OPRK1OPRD1
SCHEMBL8840558 0.90 MAPT (0.33) OPRM1OPRL1
SCHEMBL8840449 0.89 OPRM1 (0.31) OPRM1OPRL1SLC6A5
SCHEMBL8840413 0.89 OPRM1 (0.37) OPRM1OPRL1
SCHEMBL8840440 0.89
SCHEMBL8840487 0.88 OPRL1 (0.34) OPRM1OPRL1SLC6A5OPRK1
SCHEMBL9034632 0.88 OPRM1 (0.36) OPRM1OPRL1SLC6A5OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5650417-A Substituted pyridines, their preparation, and their use as pesticides and fungicides HOECHST SCHERING AGREVO GMBH (DE) 1997-07-22 US disclosed