Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910667 | 0.81 | ADRB1 (0.53) | ADRB1DNMT1PNPLMNATP53 | |
| Iodide SCHEMBL8840690 | 0.80 | ADRB1 (0.52) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL40771 | 0.71 | TP53 (0.50) | DNMT1LMNATP53HTTSMN1; SMN2 | |
| SCHEMBL5317002 | 0.71 | TP53 (0.50) | DNMT1LMNATP53HTTSMN1; SMN2 | |
| SCHEMBL16348683 | 0.69 | PIM1 (0.48) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL28121858 | 0.68 | AHCY (0.56) | TP53 | |
| SCHEMBL8840703 | 0.68 | PIM1 (0.47) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL2216449 | 0.68 | ADRB1 (0.53) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL2449672 | 0.68 | ATIC (0.56) | PDE4DPDE3ASMN1; SMN2 | |
| SCHEMBL1021989 | 0.65 | DNMT1 (0.49) | ADRB1DNMT1PNPLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652359-A | Oligonucleotides containing n-methyl thiolated bases having antiviral activity | EPOCH PHARMACEUTICALS, INC. (US) | 1997-07-29 | — | — | US | disclosed |