Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.53 |
| ▸ | PNP | P00491 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ADA | P00813 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910667 | 0.87 | ADRB1 (0.53) | ADRB1DNMT1PNPLMNATP53 | |
| Iodide SCHEMBL8840690 | 0.86 | ADRB1 (0.52) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL1021989 | 0.81 | DNMT1 (0.49) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL16348683 | 0.79 | PIM1 (0.48) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL8840703 | 0.78 | PIM1 (0.47) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL2117609 | 0.75 | ADA (0.46) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL6896687 | 0.73 | ADRB1 (0.58) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL7945679 | 0.73 | TP53 (0.62) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL15264172 | 0.72 | ADRB1 (0.51) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL9006269 | 0.71 | ADRB1 (0.58) | ADRB1DNMT1PNPLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12503466-B2 | Aminothiazole compounds as inhibitors of CTPS1 | STEP PHARMA S.A.S. (FR) | 2025-12-23 | — | — | US | disclosed |
| US-12466810-B2 | N-(5-(6-ethoxypyrazin-2-yl)pyridin-2-yl)-4-(2-(methylsulfonamido)pyrimidin-4-yl) tetrahydro-2H-pyran-4-carboxamide derivatives and related compounds as human CTPS1 inhibitors for the treatment of proliferative diseases | STEP PHARMA S.A.S. (FR) | 2025-11-11 | — | — | US | disclosed |
| US-12419940-B2 | Compositions and methods for modified dendrimer nanoparticle delivery | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-09-23 | — | — | US | disclosed |
| US-20250282756-A1 | Aminopyrimidine/pyrazine derivatives as CTPS1 inhibitors | STEP PHARMA S.A.S. (FR) | 2025-09-11 | — | — | US | disclosed |
| US-20250263407-A1 | Compounds | STEP PHARMA S.A.S. (FR) | 2025-08-21 | — | — | US | disclosed |
| US-12371419-B2 | Aminopyrimidine/pyrazine derivatives as CTPS1 inhibitors | STEP PHARMA S.A.S. (FR) | 2025-07-29 | — | — | US | disclosed |
| US-12319680-B2 | Compounds | STEP PHARMA S.A.S. (FR) | 2025-06-03 | — | — | US | disclosed |
| US-20250066324-A1 | AMINOPYRIMIDINE/PYRAZINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S.A.S. (FR) | 2025-02-27 | — | — | US | disclosed |
| US-11987573-B2 | Aminopyrimidine/pyrazine derivatives as CTPS1 inhibitors | STEP PHARMA S.A.S. (FR) | 2024-05-21 | — | — | US | disclosed |
| WO-2024040264-A1 | COMPOSITIONS AND METHODS FOR TARGETING DENDRITIC CELL LECTINS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-02-22 | — | — | WO | disclosed |
| US-8961591-B2 | Polymeric, degradable drug-eluting stents and coatings | TEPHA, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-20130190857-A1 | MEANS FOR CONTROLLED SEALING OF ENDOVASCULAR DEVICES | ENDOLUMINAL SCIENCES PTY LTD. (AU) | 2013-07-25 | — | — | US | disclosed |
| EP-1991287-B1 | POLYMERIC, DEGRADABLE DRUG-ELUTING STENTS AND COATINGS | TEPHA INC (US) | 2012-07-04 | — | — | EP | disclosed |
| US-20110190866-A1 | POLYMERIC, DEGRADABLE DRUG-ELUTING STENTS AND COATINGS | TEPHA, INC. | 2011-08-04 | — | — | US | disclosed |
| US-20110178502-A1 | CELL THERAPY FOR LIMITING OVERZEALOUS INFLAMMATORY REACTIONS IN TISSUE HEALING | ACTX, INC. | 2011-07-21 | — | — | US | disclosed |
| US-7618448-B2 | Polymeric, degradable drug-eluting stents and coatings | TEPHA, INC. (US) | 2009-11-17 | — | — | US | disclosed |
| US-20090093872-A1 | POLYMERIC, DEGRADABLE DRUG-ELUTING STENTS AND COATINGS | TEPHA, INC. | 2009-04-09 | — | — | US | disclosed |
| US-20090012604-A1 | POLYMERIC, DEGRADABLE DRUG-ELUTING STENTS AND COATINGS | TEPHA, INC. | 2009-01-08 | — | — | US | disclosed |
| US-20070185561-A1 | Polymeric, Degradable Drug-Eluting Stents and Coatings | TEPHA, INC. | 2007-08-09 | — | — | US | disclosed |
| WO-2000064918-A1 | METHOD FOR THE PRODUCTION OF 2-CHLORO-2'-DEOXYADENOSINE (CLADRIBINE) AND ITS 3,5-DI-O-p-TOLUOYL DERIVATIVE | STERRENBELD BIOTECHNOLOGIE NORTH AMERICA, INC. (US) | 2000-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371419-B2 | Aminopyrimidine/pyrazine derivatives as CTPS1 inhibitors | CTPS1, CTPS2, TYMS | ADRB1 2578/4885DNMT1 2586/4885PNP 37/4885 |
| US-12503466-B2 | Aminothiazole compounds as inhibitors of CTPS1 | CTPS1, CTPS2, TBXAS1 | ADRB1 1787/4885DNMT1 4119/4885PNP 706/4885 |
| US-12319680-B2 | Compounds | UGT1A1, CYP1A1, CYP1B1 | ADRB1 1335/4885DNMT1 2574/4885PNP 2773/4885 |
| US-20250263407-A1 | Compounds | CYP1A1, UGT1A1, CYP1A2 | ADRB1 1221/4885DNMT1 2265/4885PNP 2455/4885 |
| US-20250282756-A1 | Aminopyrimidine/pyrazine derivatives as CTPS1 inhibitors | CTPS1, CTPS2, TYMS | ADRB1 2402/4885DNMT1 2581/4885PNP 38/4885 |
| US-20250066324-A1 | AMINOPYRIMIDINE/PYRAZINE DERIVATIVES AS CTPS1 INHIBITORS | CTPS1, CTPS2, TYMS | ADRB1 2578/4885DNMT1 2586/4885PNP 37/4885 |
| US-12419940-B2 | Compositions and methods for modified dendrimer nanoparticle delivery | SARNP, RNMT, NSUN3 | ADRB1 3390/4885DNMT1 140/4885PNP 1442/4885 |
| US-11987573-B2 | Aminopyrimidine/pyrazine derivatives as CTPS1 inhibitors | CTPS1, CTPS2, TYMS | ADRB1 2578/4885DNMT1 2586/4885PNP 37/4885 |
| US-12466810-B2 | N-(5-(6-ethoxypyrazin-2-yl)pyridin-2-yl)-4-(2-(methylsulfonamido)pyrimidin-4-yl) tetrahydro-2H-pyran-4-carboxamide derivatives and related compounds as human CTPS1 inhibitors for the treatment of proliferative diseases | CTPS1, CTPS2, TYMS | ADRB1 4202/4885DNMT1 931/4885PNP 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.