Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5586637 | 0.80 | CA2 (0.43) | IAPPCA2GABRA1GABRB2ALDH1A1 | |
| SCHEMBL4779473 | 0.79 | TSHR (0.50) | CA2ALDH1A1TDP1TSHR | |
| SCHEMBL3216756 | 0.76 | CNR1 (0.47) | IAPPCA2ALDH1A1MAPT | |
| SCHEMBL4493446 | 0.76 | CA2 (0.46) | IAPPCA2GABRA1GABRB2ALDH1A1 | |
| SCHEMBL3216750 | 0.74 | CA2 (0.45) | IAPPCA2GABRA1GABRB2ALDH1A1 | |
| SCHEMBL2914269 | 0.72 | ALOX5 (0.49) | IAPPGABRA1GABRB2TDP1TSHR | |
| SCHEMBL430927 | 0.71 | CA2 (0.57) | IAPPCA2GABRA1GABRB2ALDH1A1 | |
| SCHEMBL68921 | 0.71 | IAPP (0.65) | IAPPCA2GABRA1GABRB2ALDH1A1 | |
| SCHEMBL430926 | 0.71 | GABRA1 (0.56) | IAPPCA2GABRA1GABRB2ALDH1A1 | |
| SCHEMBL36109 | 0.71 | CA2 (0.76) | CA2GABRA1GABRB2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684087-A | HEAT EXCHANGING OR STRIPPING SOLVENTS FROM SOLUTIONS OF POLYMERS WITH STEAM FOR POLYMER PASTES, CLEANING AND HEATING | BAYER AKTIENGESELLSCHAFT (DE) | 1997-11-04 | — | — | US | disclosed |