SCHEMBL4493446

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL56491	0.89	CA2 (0.58)	CA2ALDH1A1TDP1TSHRLMNA
	SCHEMBL5586637	0.84	CA2 (0.43)	CA2ALDH1A1TDP1TSHRLMNA
	SCHEMBL15068234	0.83	ALDH1A1 (0.42)	CA2ALDH1A1TDP1TSHRLMNA
	SCHEMBL2916950	0.83	CA2 (0.71)	CA2ALDH1A1TDP1TSHRLMNA
	SCHEMBL4055202	0.83	ALDH1A1 (0.45)	CA2ALDH1A1TDP1TSHRLMNA
	SCHEMBL10921220	0.83	CA2 (0.46)	CA2ALDH1A1TDP1TSHRLMNA
	SCHEMBL10849701	0.83	CA2 (0.46)	CA2ALDH1A1TDP1TSHRLMNA
	SCHEMBL77491	0.83	ALDH1A1 (0.60)	CA2ALDH1A1TDP1TSHRLMNA
	SCHEMBL29350632	0.83	ALDH1A1 (0.60)	CA2ALDH1A1TDP1TSHRLMNA
	SCHEMBL4399347	0.82	TRPA1 (0.50)	CA2ALDH1A1TDP1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.