Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411313 | 0.93 | MAPT (0.39) | MAPTKDM4ENPC1RAB9AGABRP | |
| SCHEMBL8840963 | 0.89 | GABRP (0.47) | MAPTKDM4ENPC1RAB9AGABRP | |
| SCHEMBL8840946 | 0.86 | EP300 (0.33) | MAPTKDM4ENPC1RAB9AGABRP | |
| SCHEMBL9411303 | 0.84 | NPSR1 (0.39) | MAPTKDM4ENPC1RAB9AGABRP | |
| SCHEMBL8840956 | 0.84 | GABRP (0.50) | MAPTKDM4ENPC1RAB9AGABRP | |
| SCHEMBL9411277 | 0.81 | GABRP (0.38) | MAPTKDM4ENPC1RAB9AGABRP | |
| SCHEMBL8840997 | 0.81 | KMT2A (0.33) | MAPTKDM4ENPC1RAB9AKMT2A | |
| SCHEMBL9738054 | 0.77 | MAPT (0.41) | MAPTKDM4ENPC1RAB9AGABRP | |
| SCHEMBL8840973 | 0.76 | ACHE (0.48) | MAPTKDM4ENPC1RAB9AGABRP | |
| SCHEMBL9737592 | 0.75 | MAPT (0.36) | MAPTKDM4ENPC1RAB9AGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601184-A1 | FUSED PYRIDAZINE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-15 | — | — | EP | claimed |
| US-5597918-A | ANXIOLYTIC AGENTS, SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0601184-A1 | FUSED PYRIDAZINE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-15 | — | — | EP | disclosed |