Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840946 | 0.87 | EP300 (0.33) | KMT2AMAPTEP300HDAC6NPC1 | |
| SCHEMBL9411277 | 0.87 | GABRP (0.38) | KMT2ALMNAMAPTEP300HDAC6 | |
| SCHEMBL8841001 | 0.84 | BCHE (0.31) | KMT2AMAPTEP300HDAC6NPC1 | |
| SCHEMBL8840969 | 0.81 | MAPT (0.38) | KMT2ALMNAMAPTEP300HDAC6 | |
| SCHEMBL8840963 | 0.79 | GABRP (0.47) | KMT2ALMNAMAPTEP300HDAC6 | |
| SCHEMBL9411313 | 0.79 | MAPT (0.39) | KMT2ALMNAMAPTNPC1MEN1 | |
| SCHEMBL8840985 | 0.78 | ACHE (0.34) | MAPTEP300HDAC6NPC1GAA | |
| SCHEMBL8840975 | 0.76 | NPC1 (0.32) | MAPTEP300HDAC6NPC1GAA | |
| SCHEMBL9738208 | 0.76 | GAA (0.34) | KMT2AMAPTEP300HDAC6NPC1 | |
| SCHEMBL8840956 | 0.74 | GABRP (0.50) | KMT2ALMNAMAPTEP300HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601184-A1 | FUSED PYRIDAZINE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-15 | — | — | EP | claimed |
| US-5597918-A | ANXIOLYTIC AGENTS, SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0601184-A1 | FUSED PYRIDAZINE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-15 | — | — | EP | disclosed |