Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305401 | 0.83 | CA12 (0.53) | MAPTSMN1; SMN2ALDH1A1HPGDRAB9A | |
| SCHEMBL9075646 | 0.81 | SMN1; SMN2 (0.45) | MAPTSMN1; SMN2ALDH1A1HPGDRAB9A | |
| SCHEMBL9076806 | 0.78 | MAOB (0.42) | MAPTSMN1; SMN2THRBALDH1A1HPGD | |
| SCHEMBL8841216 | 0.77 | HIF1A (0.44) | MAPTSMN1; SMN2ALDH1A1HPGDRAB9A | |
| SCHEMBL8841213 | 0.76 | KDM4E (0.41) | MAPTSMN1; SMN2THRBALDH1A1HPGD | |
| SCHEMBL764569 | 0.73 | HPGD (0.71) | MAPTSMN1; SMN2ALDH1A1HPGDRAB9A | |
| SCHEMBL9074252 | 0.72 | MAOB (0.50) | SMN1; SMN2ALDH1A1RAB9AKMT2ATUBB4A | |
| SCHEMBL31384139 | 0.70 | RAB9A (0.61) | MAPTSMN1; SMN2ALDH1A1HPGDRAB9A | |
| SCHEMBL30608268 | 0.70 | NPC1 (0.73) | MAPTSMN1; SMN2THRBALDH1A1HPGD | |
| SCHEMBL8550306 | 0.69 | MAOB (0.62) | ALDH1A1RAB9AKMT2ATUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622989-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | claimed |