Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9075646 | 0.83 | SMN1; SMN2 (0.45) | HIF1AALDH1A1HPGDRAB9AKDM4E | |
| SCHEMBL8305401 | 0.78 | CA12 (0.53) | ALDH1A1HPGDRAB9AKDM4EHSD17B10 | |
| SCHEMBL8841210 | 0.77 | MAPT (0.51) | ALDH1A1HPGDRAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL8609989 | 0.76 | ALDH1A1 (0.71) | ALDH1A1HPGDRAB9AKDM4EHSD17B10 | |
| SCHEMBL20323086 | 0.76 | RAB9A (0.54) | ALDH1A1HPGDRAB9AKDM4EHSD17B10 | |
| SCHEMBL4035087 | 0.74 | POLB (0.65) | ALDH1A1RAB9AKDM4EHSD17B10SMN1; SMN2 | |
| Water SCHEMBL9248793 | 0.72 | POLB (0.63) | ALDH1A1RAB9AKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL8544477 | 0.70 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EHSD17B10NPC1 | |
| SCHEMBL20893358 | 0.69 | L3MBTL1 (0.61) | HIF1AALDH1A1HPGDRAB9AKDM4E | |
| SCHEMBL31384139 | 0.69 | RAB9A (0.61) | ALDH1A1HPGDRAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622989-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | claimed |