Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2202444 | 0.76 | CPT2 (0.40) | LMNA | |
| SCHEMBL282108 | 0.73 | TP53 (0.41) | LMNAFDPSTP53CA12CA1 | |
| SCHEMBL9451028 | 0.73 | TP53 (0.35) | LMNAFDPSTP53CA12CA1 | |
| SCHEMBL458686 | 0.71 | PGK1 (0.33) | LMNATSHR | |
| SCHEMBL9461968 | 0.71 | LMNA (0.36) | LMNAFDPSTP53ALDH1A1TSHR | |
| SCHEMBL28486 | 0.71 | TP53 (0.42) | TP53ALDH1A1TSHR | |
| SCHEMBL2982314 | 0.70 | LMNA (0.39) | LMNAFDPSTP53ALDH1A1CA12 | |
| Phosphoric Acid SCHEMBL5917774 | 0.70 | KDM4E (0.33) | TSHR | |
| SCHEMBL8842718 | 0.70 | FDPS (0.39) | FDPSTP53 | |
| Alcohol SCHEMBL11401577 | 0.69 | FDPS (0.33) | LMNAFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5683994-A | BONE DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-11-04 | — | — | US | disclosed |