Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 5/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78574 | 0.90 | KDM4E (0.34) | PGK1PGK2LMNA | |
| Phosphoric Acid SCHEMBL5917774 | 0.88 | KDM4E (0.33) | PGK1PGK2 | |
| SCHEMBL5904251 | 0.84 | FDPS (0.32) | FDPS | |
| SCHEMBL6518484 | 0.78 | PGD (0.34) | — | |
| Cyclohexylamine SCHEMBL16059711 | 0.74 | MMP8 (0.40) | FDPS | |
| SCHEMBL8842579 | 0.69 | LMNA (0.36) | FDPSLMNA | |
| SCHEMBL2202444 | 0.69 | CPT2 (0.40) | PGK1PGK2LMNA | |
| SCHEMBL458686 | 0.69 | PGK1 (0.33) | PGK1PGK2LMNA | |
| SCHEMBL19043014 | 0.68 | FOLH1 (0.36) | LMNA | |
| SCHEMBL7082097 | 0.63 | FOLH1 (0.39) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55147295-A | — | — | None | — | — | JP | disclosed |
| JP-S55147295-A | PREPARATION OF DIPHOSPHOGLYCERIC ACID SALT | NIPPON SHINYAKU CO LTD | 1980-11-17 | — | — | JP | disclosed |