Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PTPRB | P23467 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LATS1 | O95835 | 1/20 | 0.34 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165251 | 0.81 | LMNA (0.59) | LMNACYP2D6ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL1720267 | 0.79 | TAAR1 (0.39) | LMNACYP2D6ALDH1A1HTT | |
| SCHEMBL8824455 | 0.78 | KDM4E (0.42) | LMNACYP2D6ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL11969719 | 0.78 | PYCR1 (0.38) | LMNACYP2D6ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL8824450 | 0.78 | SLC6A4 (0.50) | LMNACYP2D6ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL8824562 | 0.75 | CASR (0.46) | RAB9AALDH1A1CYP3A4L3MBTL1HTT | |
| SCHEMBL7562190 | 0.75 | ALDH1A1 (0.46) | FDPSRAB9ALMNACYP2D6ALDH1A1 | |
| SCHEMBL8842844 | 0.74 | FDPS (0.41) | FDPSRAB9ALMNACYP2D6ALDH1A1 | |
| SCHEMBL11084640 | 0.74 | POLB (0.40) | LMNACYP2D6ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL11164537 | 0.74 | KMT2A (0.48) | LMNAALDH1A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698569-A | Retroviral protease inhibitors | G. D. SEARLE & CO. (US) | 1997-12-16 | — | — | US | disclosed |