Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PTPRA | P18433 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843469 | 0.89 | NPC1 (0.55) | RAB9ANPC1SMN1; SMN2HPGDRECQL | |
| Hydrochloric Acid SCHEMBL8843578 | 0.75 | HPGD (0.52) | RAB9ANPC1SMN1; SMN2HPGDRECQL | |
| SCHEMBL5526987 | 0.75 | SMN1; SMN2 (0.53) | RAB9ANPC1SMN1; SMN2HPGDRECQL | |
| SCHEMBL11613350 | 0.74 | NPC1 (0.64) | RAB9ANPC1SMN1; SMN2HPGDRECQL | |
| SCHEMBL1696835 | 0.74 | HAT1 (0.49) | RAB9ANPC1SMN1; SMN2RECQLALDH1A1 | |
| SCHEMBL1696869 | 0.74 | HAT1 (0.49) | RAB9ANPC1SMN1; SMN2RECQLALDH1A1 | |
| SCHEMBL8285409 | 0.73 | GRM5 (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL29228688 | 0.73 | ITGB3 (0.55) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL1410181 | 0.73 | ITGB3 (0.55) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL1762209 | 0.72 | LMNA (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672615-A | MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS | NOVARTIS CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |