Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.40 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843686 | 0.86 | FDPS (0.59) | FDPSTBXAS1GGPS1BTN3A1CA12 | |
| SCHEMBL9114540 | 0.79 | FDPS (0.61) | FDPSTBXAS1GGPS1BTN3A1CA12 | |
| SCHEMBL8843708 | 0.79 | TBXAS1 (0.50) | FDPSTBXAS1GGPS1BTN3A1CA12 | |
| SCHEMBL8843691 | 0.75 | TBXAS1 (0.60) | FDPSTBXAS1 | |
| SCHEMBL8843380 | 0.74 | TBXAS1 (0.63) | TBXAS1 | |
| SCHEMBL8848903 | 0.74 | TBXAS1 (0.63) | TBXAS1 | |
| SCHEMBL27968481 | 0.71 | TBXAS1 (0.62) | FDPSTBXAS1ALDH1A1EGLN3 | |
| Methyl Alcohol SCHEMBL9715289 | 0.70 | FDPS (0.93) | FDPSGGPS1BTN3A1CA12CA2 | |
| SCHEMBL515542 | 0.69 | FDPS (1.00) | FDPSGGPS1BTN3A1CA12CA2 | |
| SCHEMBL6790628 | 0.69 | ALDH1A1 (0.59) | FDPSTBXAS1ALDH1A1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627170-A | Phosphonic acid compound containing heterocyclic substituents, pharmaceutical composition contains same and a method of treating calcium metabolism disturbance | BOEHRINGER MANNHEIM GMBH (DE) | 1997-05-06 | — | — | US | disclosed |
| US-5538957-A | OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-07-23 | — | — | US | disclosed |