Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843532 | 0.88 | FOLH1 (0.49) | ANPEPALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8842991 | 0.85 | LMNA (0.46) | ALDH1A1KMT2AMEN1L3MBTL1HDAC3 | |
| SCHEMBL8843501 | 0.84 | ANPEP (0.50) | ANPEPALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL13151639 | 0.83 | ANPEP (0.53) | ANPEPALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL1515643 | 0.79 | ALDH1A1 (0.50) | ANPEPALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL28228765 | 0.79 | EPHX1 (0.47) | KMT2AMEN1CYP1A2CYP2D6 | |
| SCHEMBL9407510 | 0.78 | MEN1 (0.56) | ANPEPALDH1A1MAPTKMT2AMEN1 | |
| Carbamic Acid SCHEMBL7552207 | 0.78 | ANPEP (0.57) | ANPEPALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL20417941 | 0.77 | ALDH1A1 (0.47) | ANPEPALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL22052987 | 0.77 | ALDH1A1 (0.47) | ANPEPALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672615-A | MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS | NOVARTIS CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |