Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8842662 | 0.83 | NFE2L2 (0.30) | — | |
| SCHEMBL8601462 | 0.81 | ALDH1A1 (0.36) | MAPTALDH1A1 | |
| SCHEMBL5906267 | 0.79 | ALDH1A1 (0.39) | MAPTALDH1A1 | |
| SCHEMBL8842637 | 0.75 | ALDH1A1 (0.38) | MAPTALDH1A1 | |
| SCHEMBL8843267 | 0.75 | — | — | |
| SCHEMBL8038796 | 0.72 | NFE2L2 (0.32) | — | |
| SCHEMBL8843336 | 0.71 | HCAR1 (0.36) | JAK2JAK1JAK3MAPK1 | |
| SCHEMBL8025205 | 0.71 | NFE2L2 (0.33) | — | |
| SCHEMBL8041713 | 0.69 | — | — | |
| SCHEMBL8842403 | 0.69 | HTT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5605920-A | HERBICIDES, SELECTIVE IN PADDY FIELDS | NIHON BAYER AGROCHEM K.K. (JP) | 1997-02-25 | — | — | US | disclosed |
| EP-0733625-A1 | 1-Substituted-tetrazolinones and their use as herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1996-09-25 | — | — | EP | disclosed |