Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5906267 | 0.98 | ALDH1A1 (0.39) | ALDH1A1MAPTKDM4EPKMADORA2A | |
| SCHEMBL8843329 | 0.81 | JAK2 (0.38) | ALDH1A1MAPT | |
| SCHEMBL8842403 | 0.78 | HTT (0.31) | — | |
| SCHEMBL8843336 | 0.77 | HCAR1 (0.36) | HCAR1 | |
| SCHEMBL8551872 | 0.76 | SRC (0.38) | HCAR1 | |
| SCHEMBL9195502 | 0.75 | ALDH1A1 (0.36) | ALDH1A1MAPTKDM4EPKMTSHR | |
| SCHEMBL8842662 | 0.75 | NFE2L2 (0.30) | — | |
| SCHEMBL8041713 | 0.74 | — | — | |
| SCHEMBL8842637 | 0.74 | ALDH1A1 (0.38) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL9556936 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MAPTKDM4EPKMADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301901-B | Tetrazolinone substituted steroids and uses thereof | 北京轩义医药科技有限公司 | 2022-09-09 | — | — | CN | disclosed |
| US-20220089636-A1 | TETRAZOLONE SUBSTITUTED STEROIDS AND USE THEREOF | BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) | 2022-03-24 | — | — | US | disclosed |
| EP-3911331-A1 | TETRAZOLONE SUBSTITUTED STEROIDS AND USE THEREOF | Beijing Xuanyi Pharmasciences Co., Ltd. (CN) | 2021-11-24 | — | — | EP | disclosed |
| CN-113301901-A | Tetrazolinone substituted steroids and uses thereof | 北京轩义医药科技有限公司 | 2021-08-24 | — | — | CN | disclosed |
| WO-2020150210-A1 | TETRAZOLONE SUBSTITUTED STEROIDS AND USE THEREOF | BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) | 2020-07-23 | — | — | WO | disclosed |
| WO-2020150210-A1 | TETRAZOLONE SUBSTITUTED STEROIDS AND USE THEREOF | BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) | 2020-07-23 | — | — | WO | disclosed |
| US-5767286-A | REACTING A TETRAZOLINONE WITH A CARBAMOYL CHLORIDE IN THE PRESENCE OF 4-DIMETHYLAMINOPYRIDINE | NIHON BAYER AGROCHEM K. K. (JP) | 1998-06-16 | — | — | US | disclosed |
| EP-0646577-B1 | Process for the preparation of 1,4-disubstituted-5(4H)-tetrazolinones | BAYER AGROCHEM KK (JP) | 1998-06-03 | — | — | EP | disclosed |
| EP-0643049-B1 | A process for the preparation of 1-substituted-5(4H)-tetrazolinones | BAYER AGROCHEM KK (JP) | 1997-05-14 | — | — | EP | disclosed |
| US-5502204-A | REACTING WITH ETHYLENE OXIDE DERIVATIVE | NIHON BAYER AGROCHEM K.K. (JP) | 1996-03-26 | — | — | US | disclosed |
| CN-1104639-A | A process for the preparation of 1-substituted-5(4H)-tetrazolinones | BAYER AGROCHEM KK (JP) | 1995-07-05 | — | — | CN | disclosed |
| CN-1102183-A | Process for the preparation of 1,4-disubstituted-5(4H)-tetrazolinones | BAYER AGROCHEM KK (JP) | 1995-05-03 | — | — | CN | disclosed |
| EP-0646577-A1 | Process for the preparation of 1,4-disubstituted-5(4H)-tetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1995-04-05 | — | — | EP | disclosed |
| EP-0643049-A1 | A process for the preparation of 1-substituted-5(4H)-tetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1995-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089636-A1 | TETRAZOLONE SUBSTITUTED STEROIDS AND USE THEREOF | CACNA1I, TAAR5, TAAR1 | ALDH1A1 525/4885MAPT 340/4885KDM4E 3659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.