Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | GLUL | P15104 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843499 | 0.83 | GABRR1 (0.40) | GABBR2GABBR1FOLH1GLULLMNA | |
| SCHEMBL8843565 | 0.79 | CPB2 (0.41) | FOLH1GLULLMNABLMALDH1A1 | |
| SCHEMBL10591466 | 0.79 | FOLH1 (0.45) | FOLH1 | |
| SCHEMBL8842809 | 0.79 | FOLH1 (0.35) | FOLH1TDP1MEN1LMNAHPGD | |
| SCHEMBL8844113 | 0.78 | GSR (0.47) | FOLH1LMNABLM | |
| SCHEMBL9462030 | 0.77 | LAP3 (0.39) | FOLH1TDP1MEN1LMNAHPGD | |
| SCHEMBL2764210 | 0.77 | TDP1 (0.56) | FOLH1TDP1MEN1LMNAHPGD | |
| SCHEMBL8844273 | 0.77 | GSR (0.46) | FOLH1MEN1LMNABLMKMT2A | |
| SCHEMBL8844107 | 0.77 | GSR (0.46) | FOLH1MEN1LMNABLMKMT2A | |
| Water SCHEMBL5161812 | 0.76 | TDP1 (0.54) | FOLH1TDP1MEN1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627170-A | Phosphonic acid compound containing heterocyclic substituents, pharmaceutical composition contains same and a method of treating calcium metabolism disturbance | BOEHRINGER MANNHEIM GMBH (DE) | 1997-05-06 | — | — | US | disclosed |
| US-5538957-A | OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-07-23 | — | — | US | disclosed |
| CN-1088931-A | New phosphonosuccinic acid derivatives and preparation method thereof and the pharmaceutical composition that contains these compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-07-06 | — | — | CN | disclosed |